December 21, 2005
Gastric Acid–Suppressive Agents Linked to Clostridium difficile Diarrhea Proton-pump inhibitors (PPIs) and H2-receptor agonists (H2RAs) are associated with increased risk for community-acquired Clostridium difficile–associated disease (CDAD), according to the results of 2 population-based, case-control studies reported in the December 21 issue of JAMA. “Recent reports suggest an increasing occurrence and severity of C. difficile–associated disease,” [...]
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December 20, 2005
Certain Drugs May Be as Effective as Surgical Management for GERD A Comparative Effectiveness Review from the Agency for Healthcare Research and Quality (AHRQ) found that medical management with certain drugs is as effective as surgical management for chronic uncomplicated gastroesophageal reflux disease (GERD). The Tufts–New England Medical Center Evidence-based Practice Center prepared this report [...]
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