Mystery novels and diagnosis

15 Oct
2009

Long time readers know that I love mystery novels.  While many literary critics look down at genre fiction, I would argue that the best mystery novels comment on society, the diagnostic process and the human condition.

I have read several mysteries recently that reminded me of the diagnostic challenge.  In many mysteries, the protagonist must look past the easy answer and struggle to find the correct answer.  I would argue that excellent internists must do this.

The big error in medicine is premature closure.  We all make this mistake, the best clinicians less often.  We have premature closure when we see an “obvious” diagnosis and proceed with that diagnosis.  We err when we start to ignore new data that do not fit the “obvious” diagnosis.

As I stated last week, “Many diagnostic errors occur because we try to fit the data to our hypothesis rather than fitting the hypothesis to our data.”

How do we avoid premature closure?  We have a responsibility to the patient to keep our minds open to alternate possibilities.  For students and residents, this error and the defense against this error explains why we obsess on differential diagnosis.  If we develop a complete differential diagnosis, then we will at least consider all the possibilities.  We who teach internal medicine are not being picayune, but rather stretching our concerns and the learners’ concerns so that we do not miss an important diagnosis.

I greatly enjoy reading a mystery novel in which the key is not superior intellect as much as a dogged persistence.  The smartest internist is not necessarily the best, unless that internist also remains dogged when the data do not make sense.

Related posts:

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  4. Our challenge – the long tail
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1 Response to Mystery novels and diagnosis

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Michael Kirsch, M.D.

October 15th, 2009 at 9:10 pm

I agree, but sometimes closure is the right answer. Clinicians who are too expansive or indecisive are handicapped. We will never reach 100% certainty of a diagnosis, and we need to know when to pull the trigger. This threshold changes in every patient, depending upon the disease severity, risk of missing a significant diagnosis, patients’ (or their family’s) demand for more certainty, fear of litigation and physicians’ style of practice. These are issues of medical judgment, which are honed over time. When I see patients with elevated liver enzymes, I don’t look for Wilson’s Disease, even though it’s on ‘the list’. While premature closure is not ideal, delayed closure is equally deleterious. http://www.MDWhistleblower.blogspot.com

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