Defining secondary prevention

6 Feb
2009

 

Our favorite Dinosaur asks a great question:

Secondary prevention is not controversial; primary prevention is very controversial.

Where exactly do you draw the line defining the difference between the two? What kind of “cardiac event” tips a patient over into secondary vs. primary prevention? Clearly a documented MI counts, but what about ACS? Is asymptomatic non-obstructing coronary disease enough of an “event”?

As I understand secondary prevention, we treat patients who have either documented coronary artery disease or a coronary artery disease equivalent (type II DM).  I clearly would treat patients with any acute coronary syndrome.  I would treat type II DM, as they generally have CAD even if we have not yet proven it. 

Asymptomatic coronary disease is the one difficult one to consider.  It is easy if they happen to also have diabetes, but let’s assume that the patient had a cardiac CT and subsequently a cath.  I would probably make my decision based on 2 other factors.  If the LDL is elevated and there are no other risk factors I would likely use a statin.  If the patient had an abnormal cardiac stress test I would probably use a statin.

When considering primary prevention I was considering patients like me.  I am old enough to be of high risk, but have no other risk factors.  I happen to have a low LDL, but I have many friends who have LDL in the 130-160 range.  Many physicians put them on statins.  I would not.  Perhaps I would now check CRP and start the statin if that were also elevated, but I do not believe the data are yet overwhelming.

The good news remains that both simvastatin and pravstatin are "Wal-Mart" drugs, so the cost implications are much more reasonable.  The fuzzy area between primary and secondary prevention represents a situation in which we need clinical judgment.  I do not believe that we have enough data for hard rules.

 

Related posts:

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