Comments on: Renin inhibitors?

By: Carmelita McNair

Carmelita McNair — Tue, 19 Oct 2010 01:59:37 +0000

my doctor prescribed aliskiren along with diovan 300mg l50 mga;iskiren because I have a debilitating itching. I am always worried about a new and powerful drug because my body does not tolerate high dosages.will these two drugs work together or will they not? I am desperate for more info. thanks., Does novartis make a blood pressure pill that does not cause itching? If so,what is it?

By: Sam G

Sam G — Mon, 30 Jun 2008 01:25:53 +0000

Chlorthalidone Man….Why not tell the reps what you want. What’s your favorite place to get your info on new stuff? Medical Letter…?

By: Chlorthalidone Man

Chlorthalidone Man — Wed, 09 Apr 2008 19:23:15 +0000

Brandon Bingham – Any thoughts?

MedRants: The other day a drug rep started to pitch the new renin inhibitor. >>>>>>>>>>>Hold Up. Bring your own lunch and don’t waste your time. The reps bring fatty food anyway and you’ll just get chubby. Reps make your brain shrink. Certainly dont see any reps until you think you might prescribe the drug, like you say, in a few years.

By: Art

Art — Tue, 08 Apr 2008 20:58:23 +0000

One thing we all should remember is that there is no one drug that fits us all. I have been on Norvasc, and HCT, and Benicar HCT (which gave me kidney failure and full Erectile dysfunction even with Cialis). I am hoping that this will solve my blood pressure and ED problems. By the way my mother takes Norvasc and is fine.

By: Brandon Bingham

Brandon Bingham — Thu, 27 Mar 2008 01:30:53 +0000

We had a drug rep visit us today and tell us that it was more effective because it stopped Renin (an earlier part in the HTN cascade) and consequently was more effective at lowering BP than ARBs or ACE-I’s. Hmmmm. Any thoughts?

By: Sandra

Sandra — Sat, 27 Oct 2007 17:28:30 +0000

From the flip side, I’ve been on every other medication for hypertension and due to strong negative and/or allergic reactions
I was getting no improvements and huge side effects. It was the 5th in line med for me and beta blockers just make me get fatter. My Dr. was pulling his hair out.
So.. I’ve had a month of the Aliskiren and my blood pressure is finally in the normal range for the first time in 6 months. I’m worried very much about the cost because it is expensive but I’m hoping that it will improve with time and that I get more samples .

By: Dr. Bob FP

Dr. Bob FP — Thu, 17 May 2007 02:12:56 +0000

Why the rush? With bisoprolol, HCTZ, & lisinopril all $4 a month Walmart meds (even combined) and with good heart failure, stroke, MI, etc. data; Aliskiren is at best a 4th line med unless it comes with some pretty amazing studies. You can control most patient’s BP with those for $8 a month with 2 pills once a day. If that’s not enough, you can throw in some generic felodipine and still be less than 1 Rx for Aliskiren.

By: joel topf

joel topf — Tue, 15 May 2007 01:24:47 +0000

Looking at the package insert it looks like the drug only caused hyperkalemia in the presence of ARB/ACEi so perhaps renin inhibitors will have a roll in patients intolerant of ACEi/ARB due to hyperkalemia.

Thoughts?