Secondary prevention of CAD

by rcentor on May 16, 2006

General internists and family physicians must become experts at secondary prevention. The AHA and ACC have released their latest guideline – Updated Secondary Prevention Guidelines Issued for CVD

For the first time, the guidelines recommend influenza vaccination for patients with chronic cardiovascular disease due to a heightened risk for complications from flu. “This is an important new addition to our guidelines that should significantly improve outcomes for patients with cardiovascular diseases,” Dr. Sidney C. Smith, Jr., of the University of North Carolina, Chapel Hill and chairman of the writing committee said in a statement.

Among the other key updates — a target LDL-cholesterol level of less than 100 mg/dL for all patients with coronary heart disease and other forms of atherosclerotic vascular disease. The guidelines also state that it is now considered “reasonable” to bring LDL-C levels to below 70 mg/dL in these patients.

Nearly 2 years ago, the National Cholesterol Education Program recommended an optional LDL-C goal of 70 mg/dL in very high-risk patients. Since that time, new data have become available that strengthen and extend this recommendation to all patients with established CHD, the committee notes. The updated guidelines also state that if triglycerides are equal to or greater than 200 mg/dL, non-HDL-C should be less than 130 mg/dL and it is reasonable to aim for a level less than 100 mg/dL.

The updated recommendation for physical activity is 30 to 60 minutes 7 days per week or a minimum of 5 days per week. The earlier guidelines called for 30 to 60 minutes of exercise three or four times per week.

The updated guidelines also recommend complete smoking cessation and no exposure to environmental tobacco smoke; BP < 140/90 mm Hg; if the patient has diabetes or chronic kidney disease, BP < 130/80 mm Hg is the goal.

For weight management, the goal remains a body mass index of 18.5 to 24.9 kg/m2 and a waist circumference < 40 inches for men and < 35 inches for women.

For diabetic patients, hemoglobin A1c levels should be less than 7 percent, according to the guidelines.

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{ 3 comments… read them below or add one }

steve,md May 16, 2006 at 11:34 am

Note that the level of evidence for a target LDL-C less than 70 is IIA vs level of evidence IA for target less than 100.
Also note that 11 of 14 of the writers of these guidelines report potential conflicts of interest.
So think twice or 3 times before pushing to the lower target.
Finally, I wonder if we’re not setting our patients up for failure by recommending 30-60 min of exercise 7days per week. I think they’ll be more likely to pursue a more achievable goal.

Dr. Bob May 16, 2006 at 9:53 pm

I agree with most except the goal of a BMI 18.5-25. All the NHANES data shows that the lowest mortality is a BMI of 25-30. Some recent studies from China show the lowest mortality to be b/w 24-27. BMI is a pretty crummy measure of adiposity vs. muscle mass. More emphasis should be placed on waist circumference (that’s why all the risk calculators use that rather then BMI).

Steve Lucas May 17, 2006 at 7:12 am

I have been caught in the BMI trap. With a 46″ chest and 34″ waist I have been told I need to loose 20+ pounds to reach a BMI of 20 or below by a number of doctors or I will have a stroke. This is followed by my standing up and forcing the doctor to look at me and tell me where I can loose the weight. I cannot emphasis enough the importance of the good old fashion physical, at least look at your patients.

My understanding is the current weight charts were done with information on international weights with an emphasis on third world countries. This would skew EU and US weights to the high side.

My problem with the recommendations is doctors do not use them, instead using numbers provided by the pharmaceutical companies. Many doctors will tell you a BP 120/80 is high and a LDL of 70 is required of all patients. These doctors are very willing to medicate and test until you reach these levels regardless of the current or long term side effects.

Needless to say my doctor hates me as I rattle off these numbers and throw in numbers needed to treat. Particularly annoying is when I ask for the confirming numbers on an odd reading. For the last 20 years every doctor I have seen has had a variation on “We need to get you medicated so we can get you in more often.” This has been accompanied by attempts at physical intimidation and on more than one occasion physically blocking me from leaving the examination room.

Thank you for getting this information out.

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