More on C Diff


Category : Clinical articles, General, Medical Rants

A few weeks ago I wrote about quinolones being a risk factor for C Diff (C Diff stands for Claustridium Difficile) diarrhea. Over the past few years, C Diff has gone from being a diagnosis that we consider only after antibiotics to one which occurs spontaneously. Thus, C Diff now enters the differential diagnosis in community acquired severe diarrhea.

Highlights From MMWR: C. difficile-Associated Disease in Young, Healthy Individuals and More

The Centers for Disease Control and Prevention (CDC) reported in the Dec. 2 issue of the Morbidity and Mortality Weekly Report on 33 cases of severe Clostridium difficile–associated disease in peripartum women and healthy individuals with minimal or no exposure to a healthcare setting; a 31% decrease in the incidence of early-onset perinatal invasive group B streptococcal disease that has been attributed to implementation of universal screening guidelines in 2002; an increased risk for very low birthweight infants among younger and older mothers; and a continued low prevalence of adults engaging in minimum recommended levels of physical activity.

Clostridium difficile–Associated Disease Reported in Young, Healthy Individuals

The CDC has reported on 33 cases of severe Clostridium difficile–associated disease (CDAD) occurring in healthy individuals living in the community and peripartum women, two populations previously thought to be at low risk. C difficile has typically affected older or severely ill hospital inpatients or residents of long-term care facilities.

Other uncommon features observed in these cases that reflect the changing epidemiology of CDAD include close-contact transmission, high recurrence rate, young patient age, bloody diarrhea, and lack of antimicrobial exposure.

Next week’s New England Journal of Medicine will carry two articles about this problem, plus an editorial. This is an important infectious disease of which all physicians must increase their awareness.

Today’s NY Times also addresses the problem –Deadly Germ Is Becoming Wider Threat

This is not a scare – but rather a very important health problem.

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Comments (3)

Thanks for this post. I wonder if this has any relation to the Quebec strain. I blogged about the Quebec strain this evening.

[…] The “grounds” are hosted by Dr. Charles this week. Hmmm, they missed the links/updates on C. difficile that DB did. […]

On 12/2/05, my 64 year old sister died. On 11/23/05, she’d had to clean up our mother’s bathroom, following an episode of diarrhea from our mother. Our mother had been hospitalized in late October or early November, 05 for pneumonia and had severe constipation, so had had ememas at the hospital, Banner Baywood at Mesa, AZ. But, following that hospital stay, she had diarrhea, which was diagnosed, possibly after 11/23/05 as C-diff. Our mother continues to battle the disease. My sister had an annurism on 11/23/05, as she was at the hospital to bring our mother back home from the ER. At what point, she was diagnosed with C-diff, also, I don’t know, but had been diagnosed with it by 11/28/05. I don’t know if she’d have died from the annurism, following her brain surgery or not, if she hadn’t had to also be dealing with the C-diff. I am a nurse, who’s worked in nursing homes, so knew right away what we were dealing with, though the nursing staff only made light of it at the hospitals where our mother and sister were confined. Our sister was at Banner Good Samaritan, Phoenix, AZ.

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