Comments on: Vioxx recalled

By: Subaqua Sternal Rubs » Blog Archive » Merck recalls Vioxx

Subaqua Sternal Rubs » Blog Archive » Merck recalls Vioxx — Sun, 22 May 2005 18:24:37 +0000

[...] overed the higher heart risk compared to patients taking dummy pills. Seen at: Kevin, MD DB’s Medical Rants Rangel, MD [...]

By: Drug Vioxx

Drug Vioxx — Tue, 09 Nov 2004 15:11:22 +0000

Agreed, I have seen several comments and concerns raised regarding Vioxx. Sort of troublesome to know this is possible, something once safe now harmful.

By: Overlawyered

Overlawyered — Fri, 08 Oct 2004 02:49:05 +0000

Vioxx medblog roundup
There’s been plenty of discussion going on among the medical bloggers about Merck’s withdrawal of its arthritis drug. For posts especially relating to the courtroom implications, follow the italics: Derek Lowe (first, second posts); KevinMD (lots of …

By: pj

pj — Sun, 03 Oct 2004 23:53:11 +0000

merck estimates US sales of vioxx to be 2 billion annually.
(roughly that equates to 2 million prescriptions/year.)

from a generalist perspective of seeing numerous NSAID related complication over the past 12 years, “older”
NSAIDs have a lot of risk in themselves. GI Bleeding, fluid retention precipating overt Congestive Heart failure, renal failure , liver inflammation…etc…

Older NSAID’s despite this are my preferred meds but I must admit when patients seemed at very high risk for GI bleeding and had severe arthritis my choices were limited. Cox 2 seemed like a break through. it is scary to see someone transfused with several units of blood, NG tube, cardiac monitor or ICU and then telling a loved one that the GI bleed led to a Heart attack.

Narcotics have their own multiple attendent risks,

it seems like we are back to NSAIDs and narcotics.
is this good or bad?

By: Bernie Simon

Bernie Simon — Sat, 02 Oct 2004 00:26:40 +0000

I was never convinced of the value of this class of drugs (Cox-2 inhibitors) over plain old NSAIDs, especially in light of recent evidence that they’re harder on the stomach than originally supposed.

OT link of the day: medical students find their education
humiliating.

By: swift

swift — Fri, 01 Oct 2004 18:14:17 +0000

Evidence indicating these same sorts of adverse cardiovascular effects for Vioxx was published in JAMA in 2001. Nevermind Merck or the FDA, aren’t the physicians who prescribed this drug just as liable? Shows what you get when you rely on drug reps for your CME. With a nod to the impact of the religious right on the news media landscape, I’m afraid that all those who have written scripts for this drug these past three years may end up burning in hell for their part in this travesty.

By: Stef

Stef — Thu, 30 Sep 2004 17:57:04 +0000

Should we worry about Celebrex as well?
Is there any theoretical reason that Vioxx would be more susceptible to this problem than Celebrex?

By: Subaqua Sternal Rubs » Merck recalls Vioxx

Subaqua Sternal Rubs » Merck recalls Vioxx — Thu, 01 Jan 1970 00:00:00 +0000

[...] overed the higher heart risk compared to patients taking dummy pills. Seen at: Kevin, MD DB’s Medical Rants Rangel, MD