Vioxx recalled
September 30, 2004
I generally resist new medications. Most 55 year old physicians do. I know the old drugs well. And I have seen too many new drugs withdrawn from the market after side effect reporting.
Many of my friends took Vioxx. The name is just so cool. 2 XXs – wow. But the coolness and promise of this drug now becomes history – Merck Announces Withdrawl of Vioxx Painkiller
Pharmaceutical giant Merck & Company is pulling its blockbuster arthritis drug Vioxx from the market worldwide because new data from a clinical trial found an increased risk of heart attack and stroke.
Whitehouse Station-based Merck said Thursday that data from the trial showed the increased risk of heart attack and other cardiovascular complications began 18 months after patients started taking Vioxx.
The data comes from a three-year study aimed at showing that Vioxx at a 25 milligram dose prevents recurrence of polyps in the colon and rectum. The trial was stopped after Merck discovered the higher heart risk compared to patients taking dummy pills.
free viagra
buy viagra online
generic viagra
how does viagra work
cheap viagra
buy viagra
buy viagra online inurl
viagra 6 free samples
viagra online
viagra for women
viagra side effects
female viagra
natural viagra
online viagra
cheapest viagra prices
herbal viagra
alternative to viagra
buy generic viagra
purchase viagra online
free viagra without prescription
viagra attorneys
free viagra samples before buying
buy generic viagra cheap
viagra uk
generic viagra online
try viagra for free
generic viagra from india
fda approves viagra
free viagra sample
what is better viagra or levitra
discount generic viagra online
viagra cialis levitra
viagra dosage
viagra cheap
viagra on line
best price for viagra
free sample pack of viagra
viagra generic
viagra without prescription
discount viagra
gay viagra
mail order viagra
viagra inurl
generic viagra online paypal
generic viagra overnight
generic viagra online pharmacy
generic viagra uk
buy cheap viagra online uk
suppliers of viagra
how long does viagra last
viagra sex
generic viagra soft tabs
generic viagra 100mg
buy viagra onli
generic viagra online without prescription
viagra energy drink
cheapest uk supplier viagra
viagra cialis
generic viagra safe
viagra professional
viagra sales
viagra free trial pack
viagra lawyers
over the counter viagra
best price for generic viagra
viagra jokes
buying viagra
viagra samples
viagra sample
cialis
generic cialis
cheapest cialis
buy cialis online
buying generic cialis
cialis for order
what are the side effects of cialis
buy generic cialis
what is the generic name for cialis
cheap cialis
cialis online
buy cialis
cialis side effects
how long does cialis last
cialis forum
cialis lawyer ohio
cialis attorneys
cialis attorney columbus
cialis injury lawyer ohio
cialis injury attorney ohio
cialis injury lawyer columbus
prices cialis
cialis lawyers
viagra cialis levitra
cialis lawyer columbus
online generic cialis
daily cialis
cialis injury attorney columbus
cialis attorney ohio
cialis cost
cialis professional
cialis super active
how does cialis work
what does cialis look like
cialis drug
viagra cialis
cialis to buy new zealand
cialis without prescription
free cialis
cialis soft tabs
discount cialis
cialis generic
generic cialis from india
cheap cialis sale online
cialis daily
cialis reviews
cialis generico
how can i take cialis
cheap cialis si
cialis vs viagra
levitra
generic levitra
levitra attorneys
what is better viagra or levitra
viagra cialis levitra
levitra side effects
buy levitra
levitra online
levitra dangers
how does levitra work
levitra lawyers
what is the difference between levitra and viagra
levitra versus viagra
which works better viagra or levitra
buy levitra and overnight shipping
levitra vs viagra
canidan pharmacies levitra
how long does levitra last
viagra cialis levitra
levitra acheter
comprare levitra
levitra ohne rezept
levitra 20mg
levitra senza ricetta
cheapest generic levitra
levitra compra
cheap levitra
levitra overnight
levitra generika
levitra kaufen
Related Posts
- An interesting perspective on the Vioxx damage award
- The New Yorker comments on the Vioxx lawsuits
- Risks and benefits – what if Merck starts selling Vioxx again?
- Another comment on Vioxx (now revised)
- More on Vioxx
Related posts brought to you by Yet Another Related Posts Plugin.
Posted in Medical Rants, Pharma
content rss
September 30th, 2004 at 10:49 pm
[...] overed the higher heart risk compared to patients taking dummy pills. Seen at: Kevin, MD DB’s Medical Rants Rangel, MD
September 30th, 2004 at 1:57 pm
Should we worry about Celebrex as well?
Is there any theoretical reason that Vioxx would be more susceptible to this problem than Celebrex?
October 1st, 2004 at 2:14 pm
Evidence indicating these same sorts of adverse cardiovascular effects for Vioxx was published in JAMA in 2001. Nevermind Merck or the FDA, aren’t the physicians who prescribed this drug just as liable? Shows what you get when you rely on drug reps for your CME. With a nod to the impact of the religious right on the news media landscape, I’m afraid that all those who have written scripts for this drug these past three years may end up burning in hell for their part in this travesty.
October 1st, 2004 at 8:26 pm
I was never convinced of the value of this class of drugs (Cox-2 inhibitors) over plain old NSAIDs, especially in light of recent evidence that they’re harder on the stomach than originally supposed.
OT link of the day: medical students find their education
humiliating.
October 3rd, 2004 at 7:53 pm
merck estimates US sales of vioxx to be 2 billion annually.
(roughly that equates to 2 million prescriptions/year.)
from a generalist perspective of seeing numerous NSAID related complication over the past 12 years, “older”
NSAIDs have a lot of risk in themselves. GI Bleeding, fluid retention precipating overt Congestive Heart failure, renal failure , liver inflammation…etc…
Older NSAID’s despite this are my preferred meds but I must admit when patients seemed at very high risk for GI bleeding and had severe arthritis my choices were limited. Cox 2 seemed like a break through. it is scary to see someone transfused with several units of blood, NG tube, cardiac monitor or ICU and then telling a loved one that the GI bleed led to a Heart attack.
Narcotics have their own multiple attendent risks,
it seems like we are back to NSAIDs and narcotics.
is this good or bad?
October 7th, 2004 at 10:49 pm
Vioxx medblog roundup
There’s been plenty of discussion going on among the medical bloggers about Merck’s withdrawal of its arthritis drug. For posts especially relating to the courtroom implications, follow the italics: Derek Lowe (first, second posts); KevinMD (lots of …
November 9th, 2004 at 9:11 am
Agreed, I have seen several comments and concerns raised regarding Vioxx. Sort of troublesome to know this is possible, something once safe now harmful.
May 22nd, 2005 at 12:24 pm
[...] overed the higher heart risk compared to patients taking dummy pills. Seen at: Kevin, MD DB’s Medical Rants Rangel, MD [...]